PET/CT is approved by Medicare for use in staging, restaging and detecting recurrence in Hodgkins and Non-Hodgkins lymphoma.
PET/CT has also been shown to be an accurate tool for measuring response to therapy after the first cycle (Spaepen et al, 2001).
1.Spaepen etal. Prognostic value of PET with FDG after first line chemotherapy in NHL: Is FDG a valid alternative to conventional diagnostic modalities? Journal of Clinical Oncology, Vol 19, No 2 2001 414-419.
2004 Lymphoma Statistics*
Estimated New Cases
- Non Hodgkin’s Disease 7,880
- Hodgkin’s Disease 54,370
Estimated New Deaths
- Non Hodgkin’s Disease 1,320
- Hodgkin’s Disease 19,410
*All cancer statistics obtained from the American Cancer Society’s Cancer Facts and Figures available at www.cancer.org
Lymphoma & FDG PET Imaging Statistics**
Table 1: Utility of PET Imaging in Diagnosis of Lymphoma (N=11)
Table 2: Utility of PET Imaging in Lymphoma Diagnosis/Staging (N=254)
For this patient population there was a 5% change in the physician managed the patient’s disease based upon the results of the PET scan.
Table 3: Utility of PET Imaging in Lymphoma Staging (N=1796)
For this patient population there was a 21% change in the way the physician managed the patient’s disease based upon the results of the PET scan.
Table 4: Utility of PET Imaging in Lymphoma Recurrence (N=581)
For this patient population there was a 10% change in the way the physician managed the patient’s disease based upon the results of the PET scan.
Table 5: Utility of PET Imaging in Lymphoma Monitoring (N=279)
** Reprinted by permission of the Society of Nuclear Medicine from: Gambhir, Sanjiv S., Czernin, Johannes, Schwimmer, Judy, Silverman, Daniel H.S., Coleman, R. Edward, Phelps, Michael E. “A Tabulated Summary of the FDG PET Literature” J Nucl Med 2001 42: 1-93.
Patient: 13yo male with diffuse large cell lymphoma. PET/CT was used to assess response to the first cycle of therapy.
Results: PET/CT demonstrated that the chemotherapy was working. Patient completed chemo and remained disease free 2 years after completion.